Manchester United sealed their place in the quarter finals with the historic 3-1 win against Paris Saint-Germain, while Liverpool dumped Bayern Munich out of the Champions League.
Manchester City thrashed hapless Schalke 10-2 on aggregate. Ajax and Porto remain the outsiders, despite both clubs claiming the noteworthy scalps of Real Madrid and Roma in the last round, while Juventus represent one to avoid given their Cristiano Ronaldo inspired comeback against Atletico Madrid.
With the restrictions on teams from the same country facing each other now lifted, the prospect of an all-English quarter final becomes a real possibility.
The draw takes place in Nyon on Friday.