The German has a fully fit squad to choose from for the visit of the Hammers.
Dejan Lovren, Joel Matip and Ragnar Klavan are in competititon to partner Virgil van Dijk at centre-back, while Emre Can, Jordan Henderson, Georginio Wijnaldum, Alex Oxlade-Chamberlain, Adam Lallana and James Milner are competing for just three central midfield berths. Only Clyne is unlikely to feature just yet as he will need some time to regain full fitness after the back injury
The Reds are unbeaten in 15 Premier League matches at Anfield since losing to Crystal Palace in April.
The Hammers are unbeaten in their last three away games in all competitions against Liverpool. However, their only victory in the past 48 attempts at Anfield came in August 2015.