Chelsea go in search of a sixth Europa League Group L win from six games against Vidi with a host of first-choice players rested.
Kepa Arrizabalaga, Antonio Rudiger, Eden Hazard, Cesar Azpilicueta and N'Golo Kante are rested and have not travelled to Budapest, while Mateo Kovacic, Gary Cahill and Victor Moses are injured.
Chelsea [4-3-3]: Caballero, Zappacosta, Ampadu, Christensen, Emerson, Loftus-Cheek, Fabregas, Barkley, Pedro, Morata, Hudson-Odoi