Manchester United won the Europa League under Jose Mourinho in 2017 and Ole Gunnar Solskjaer will be eyeing success this time around.
The draw for the group stage takes place on Friday with some big-hitters from across Europe taking their places.
United have been drawn in pot one meaning they cannot face the likes of Roma, Sevilla or Porto.
Pot 2
PSV, Krasnodar, Celtic, Copenhagen, Braga, Gent, Borussia Monchengladbach, Young Boys, Astana, Ludogorets, APOEL, Eintracht Frankfurt
Pot 3
Saint-Etienne, Qarabag, Feyenoord, Getafe, Espanyol, Malmo, Partizan, Standard Liege, Rennes, Rosenborg, Istanbul Basaksehir
Pot 4
AZ Alkmaar, Vitoria, Trabzonspor, Olexandriya, Dudelange, LASK, Wolfsberger, Slovan Bratislava, Lugano, Rangers, Cluj, Ferencvaros
When are the matches?
- Matchday 1 - September 19
- Matchday 2 - October 3
- Matchday 3 - October 24
- Matchday 4 - November 7
- Matchday 5 - November 28
- Matchday 6 - December 12